Attenuation in the liver and in both hyperattenuating and hypoattenuating lesions did not differ between mono and mono+ (P = 0.41-0.49 The cumulative attenuation conversion rates for the 60 hypoattenuating lesions were 15.8%, 44.3%, and 58.7% at 1, 2, and 3 years. We do not endorse non-Cleveland Clinic products or services. 1. They can advise you about whether any particular treatment is needed. Noncancerous, or benign, liver lesions are common. Liver lesions are abnormal growths of liver cells that can be cancerous or noncancerous. A hyperechoic liver lesion on ultrasound can arise from a number of entities, both benign and malignant. Advertising on our site helps support our mission. Wolters Kluwer Health Any serious liver disease would be detected by mri. If benign liver lesions are large and cause symptoms, they can be removed by surgery. Diffuse hepatic steatosis , also known as fatty liver, is a common imaging finding and can lead to difficulties assessing the liver appearances, especially when associated with focal fatty sparing. They flow through a tiny tube called a catheter into the. The liver is an essential organ that plays a key role in your health. to maintaining your privacy and will not share your personal information without Treatment for liver cancer depends on factors such as: The 5-year survival rate of liver cancer continues to rise in the United States. According to the American Cancer Society, liver cancer often doesnt cause symptoms until the late stages. Additional possible causes of liver lesions include: The cause of benign lesions can vary depending on the type of lesion: Anybody can develop liver lesions, but some people are at a higher risk than others. For potential or actual medical emergencies, immediately call 911 or your local emergency service. This is again correlated with the liver function tests and clinical symptoms/history. I would be concerned about chronic liver inflammation or fat in liver that is dense or produces excess sound waves on. 7. I agree. Our mission is to help you understand your radiology reports by explaining complex medical terms in plain English. Become a Gold Supporter and see no third-party ads. Symptoms of a liver cyst. To learn more, please visit our. Get prescriptions or refills through a video chat, if the doctor feels the prescriptions are medically appropriate. Liver lesions are abnormal growths of liver cells that can be cancerous or noncancerous. People with PLD are born with it, but usually do not have large . This chapter will focus on the role of ultrasound in the diagnosis and management of pediatric hepatic disorders, including a review of transducer selection and imaging techniques, liver development and anatomy, and an overview of the most clinically relevant anatomical variants, congenital anomalies, as well as benign and malignant . A radiologist goes through medical school just like any other doctor. Sometimes a part of the liver tissue may become hypodense as compared to the nearby tissue due to focal fatty changes or due to primary or secondary tumors. i noticed on my results from a ct scan that i have a tiny hypoattenuating lesion on my liver. Can a lesion on the liver be from a fatty liver? Polycystic liver disease (PLD) is the development of multiple cysts in the liver. Malignant lesions are cancerous. Most lesions are noncancerous and dont require treatment if theyre small and dont cause symptoms. The brighter area on the image of the organ indicates some sort of abnormality to the surface. Management of incidental liver lesions on CT: A white paper of the ACR Incidental Findings Committee. The probe will give off a certain kind of energy that heats up and kills cancerous cells. CONCLUSION. Wien Klin Wochenschr. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Smoking Pot Every Day Linked to Heart Risks, Artificial Sweetener Linked to Heart Risks, FDA Authorizes First At-Home Test for COVID and Flu, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox. shoulder pain. Find the latest information from the globally recognized leader in digestive diagnosis, treatments and surgical innovations. 1 The CAR Working Group . Llovet JM, et al. History should focus on risks for chronic liver disease (parenteral exposures - transfusions, tattoos, injection drug use), alcohol consumption, symptoms of chronic liver disease (abdominal . Minimize fats - saturated fats, trans-fats, and fermented foods can aggravate symptoms, such as bloating Dandelion root - helps to alleviate some of the symptoms linked to cysts Lemon juice -. Radiographics. Treatments for liver cancer include: Its difficult to prevent benign liver lesions. They do not pose a threat themselves; however, they can easily be mistaken for other malignant lesions in radiographic images. You might not know you have them. (2020). Most people who have benign or cancerous liver cysts never have symptoms. Conclusion: Hypoattenuating hepatic nodular lesions in chronic liver disease depicted on dynamic CT have high malignant potential and should be followed with special attention to conversion from hypoattenuation to hyperattenuation to determine the optimal timing of treatment. Jang, Hyun-Jung; Lim, Hyo K.; Lee, Won Jae; Lee, Soon Jin; Yun, Jee Yeong; Choi, Dongil. The hypodense (darker) nodule in the liver could be due to a tumor, cyst or sometimes hemangioma. What Does IT Mean: Can Not Exclude Something? 1987;38 (1): 101-2. Keywords: dynamic CT, hepatocarcinogenesis, liver disease, oncologic imaging Jang, H. K. Lim, W. J. Lee, S. J. Lee, J. Y. Yun, D. Choi); and Department of Radiology and Center for Liver Cancer, National Cancer Center, Gyeonggi-do, Korea (H-J Jang). liver and gall bladder normal. Liver lesions: Types, risk factors, investigations and treatment. Learn how we can help Reviewed Oct 28, 2022 Thank Dr. Frank Kuitems agrees 1 thank Dr. Birendra Tandan answered Urology 35 years experience Read More heartburn. The presence of a hypoattenuating lesion can either mean that there is a simple cyst or small sore on the surface of the organ, or it could indicate the presence of a tear or much more serious issue such as a malignant tumor. Because a small liver cyst doesn't usually cause symptoms, it can go undiagnosed for years. may email you for journal alerts and information, but is committed Is an enhancing lesion in the lateral segment left lobe of the liver something to be concerned about? Liver lesions are often discovered through imaging tests. Liver cancers always need treatment. Does 11 mm foci in liver need further follow up? Commonly, diffuse hepatic steatosis is indicative of fatty liver disease. Doctors typically provide answers within 24 hours. What are hypodense subcapsular metastic liver lesions ? Hypoattenuating hepatic nodular lesions in chronic liver disease depicted Liver lesions are abnormal growths that have various causes. We avoid using tertiary references. Although most lesions arent harmful, its still critical to receive a proper diagnosis. Saunders Ltd. (2003) ISBN:0702026506. Those who do may have the following symptoms: Dull pain in the upper right area of their bellies. A hemangioma was defined as a hypoattenuating lesion with peripheral nodular globular enhancement and centripetal fill-in. Hypoattenuating lesion in these organs tells us nothing about the diagnosis alone. Benign liver lesions rarely grow, and they do not spread. It varies based on the type of cancer and how long the cancer has been there. The liver has a dual blood supply from both the hepatic artery (25% of the flow) and portal vein (70% of hepatic blood flow) Arterial blood is carried by the hepatic artery. Interpret the result Customer reply replied 1 year ago. Get prescriptions or refills through a video chat, if the doctor feels the prescriptions are medically appropriate. Nonalcoholic fatty liver disease (NAFLD) is evidence of hepatic steatosis (imaging or histologic) in the absence of secondary causes of hepatic fat accumulation, such as significant alcohol consumption. 10. You're fine. Educational text answers on HealthTap are not intended for individual diagnosis, treatment or prescription. few tiny foci 6mm in gall bladder. . Lawrence EM, Pooler BD, Pickhardt PJ. Search for Similar Articles Eat these 11 foods for optimal liver, Rock musician David Crosby died this month at age 81. Although your liver itself doesn't feel pain, problems in your liver can cause pain or discomfort in other places, usually throughout your abdomen. Reference article, Radiopaedia.org (Accessed on 04 Mar 2023) https://doi.org/10.53347/rID-12593. Get useful, helpful and relevant health + wellness information. Your message has been successfully sent to your colleague. The main focus of the working group was to expand upon the body of work produced by the ACR on the management of incidental imaging findings. The top risk factor for liver cancer is chronic viral hepatitis. Hypoattenuating lesions in the pelvis can be seen in organs like the uterus and ovaries. You can read the full text of this article if you: Keywords Is A Non Contrast CT Of The Abdomen Enough. Although primary liver tumors are mostly hypervascular, there are exceptions. no financial relationships to ineligible companies to disclose. Radiologic and pathologic features of common and/or critical tumor or tumor-like diagnoses (lesions) of the liver are discussed within. Had an ultrasound done last week and the results showed multiple echogenic foci identified in the liver and spleen. Keep reading to learn more about how liver lesions are classified, what causes them, and when treatment is needed. For more information, please refer to our Privacy Policy. It's always must be clinical correlation with radiology Benign tumors /neoplasms of the liver are not cancerous; malignant tumors are. Note the absence of vascular invasion. Many people only find out they have one when they go for an imaging test, like an ultrasound, for a different health issue. A cyst of 5 mm is quite common for people above 30 years old. HealthTap uses cookies to enhance your site experience and for analytics and advertising purposes. Cystic lesions of the liver in the adult can be classified as developmental, neoplastic, inflammatory, or miscellaneous. Hyperattenuating signs are occasionally observed when an acute clot has formed in a vessel and can be seen in various vascular diseases, including acute arterial occlusion, acute arterial dissection, aneurysm rupture, and acute venous thrombosis. As stated on MedPix, blood clots and tumors in the brain appear whiter than brain matter. Hypovascular liver tumors are more common than hypervascular tumors. Liver is divided in eight functionally independent segments and numbered one to eight. Last reviewed by a Cleveland Clinic medical professional on 05/18/2021. Hyperattenuating signs are occasionally observed when an acute . Ultrasound said gall bladder,liver,spleen normal. Other ways you may be able to lower your risk of developing liver lesions include: Liver lesions are common. Answer (1 of 3): A cyst was defined as a well-circumscribed lesion with an attenuation value of 20 to +20 HU. They require treatment to keep them from spreading. I had this same test done in 2018 and nothing showed up at all for Liver? Terminology The term 'fatty infiltration of the liver' is often erroneously used to describe liver steatosis. Become a Gold Supporter and see no third-party ads. Top answers from doctors based on your search: Created for people with ongoing healthcare needs but benefits everyone. Hypoattenuating lesions in the ovaries can be cysts or masses. The association between the presence, size, and number of small hypoattenuating hepatic lesions at initial CT and the subsequent development of metastases was analyzed by using Kaplan-Meier analysis. For these, please consult a doctor (virtually or in person). Check for errors and try again. Its very rare in the U.S. Dr. Carlo Hatem answered Pulmonary Critical Care 27 years experience Usually yes: There are features on your test that can give you an idea if these lesions are concerning or not. Transverse ultrasound image of liver shows multiple echogenic foci with comet-tail artifact (arrows). I assume the report includes other verbage, but what phrase you are questioning is an observation by the radiologist that the liver is not fatty nor h Hello,. Liver imaging. Other healthier lifestyle habits are far. The prevalence (25.5%) of SLAH on helical CT was higher than that reported on conventional CT; however, metastases only presenting as SLAH were rare (2.2%). It needs further . Cyst can Liver lesions implies that there are areas where the homogeneity of the liver is not complete. This can represent something like a cyst or solid nodule. hepatic hemangioma : commonest hyperechoic liver lesion by far . The finding was multiple hypoattenuating foci in the right lobe of the liver. "the liver demonstrates homogeneous signal intensity without focal lesion"? Publication types Research Support, N.I.H., Extramural MeSH terms Adult Aged Connect with a U.S. board-certified doctor by text or video anytime, anywhere. 4,260 satisfied customers. Mergo PJ, Ros PR, Buetow PC et-al. They are usually small and occur in up to 20% of humans. Triglycerides occupy 5% of the liver weight under normal conditions. This would include everything from benign lesions such Dr. Bruce J. Stringer and 2 doctors agree. Among SLAHs in patients who had SLAHs only, 14 lesions (1.6%) in 6 patients (2.2%) were metastases. Nausea and vomiting. 5. Check with your doctor. Liver lesions have a broad spectrum of pathologies ranging from benign liver lesions such as hemangiomas to malignant lesions such as primary hepatocellular carcinoma and metastasis. We explain what causes them and how theyre treated. Liver lesions are any abnormal growths on your liver. a-c: tumoral infiltration of the left liver mimicking localised steatosis. But if its cancer, effective therapy may save your life. Its sometimes found in drinking water. Diagnostic difficulties may be encountered in the characterization of. What percentage of kidney lesions are cancerous? diffused fatty liver change,mild For instance, a liver cyst and a liver abscess are both benign issues that may not require surgery, or can be removed fairly easily if they are limiting the function of the liver. Many questions. 9500 Euclid Avenue, Cleveland, Ohio 44195 |, Important Updates + Notice of Vendor Data Event, (https://liverfoundation.org/for-patients/about-the-liver/diseases-of-the-liver/benign-liver-tumors/#information-for-the-newly-diagnosed), (https://patient.info/doctor/benign-liver-tumours), (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338186/). However, a biopsy may be needed in difficult cases. American Liver Association: Benign Liver Tumors., Cleveland Clinic: Malignant Hepatic Lesions., California Pacific Medical Center: Metastatic Liver Lesions Diagnosis and Treatment, Non-Cancerous Liver Lesions Diagnosis and Treatment., Memorial Sloan Kettering Cancer Center: Liver Cancer Prevention & Risk Factors.. Benign lesions are noncancerous. Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other abusable medications. A wide spectrum of disorders can affect the pediatric liver. liver lesions shrank. why not say minor gall stones. Hepatocellular lesions (focal nodular hyperplasia, hepatocellular adenoma, hepatocellular carcinoma, and hepatoblastoma), biliary lesions (mucinous cystic neoplasm and intrahepatic cholangiocarcinoma), vascular mesenchymal lesions (cavernous hemangioma . Theyre found in as many as 30 percent of people over the age of 40. What is a Hypoattenuating hepatic lesion? On rare occasions, they can become large enough to press on nearby organs. Hypovascular metastases are the most common and occur in GI tract, lung, breast and head/neck tumors. Most hypovascular lesions are malignant and metastases are by far the most common. Presence of a layer of ascites. Educational text answers on HealthTap are not intended for individual diagnosis, treatment or prescription. Kodama Y, Ng CS, Wu TT et-al. It is also called fatty liver, fatty metamorphosis, or steatosis of the liver. The spot is too small to differentiate. The term is used by radiologists to describe the abnormality to someone reading the report. If tumors grow large, they may cause symptoms and need to be removed. AJR Am J Roentgenol. This is the American ICD-10-CM version of R93.2 - other international versions of ICD-10 R93.2 may differ. What does focal tiny echogenic foci whithin the liver pranchima mean for 2month old baby ( he was born on his 7th month premature) ? (2021). Top answers from doctors based on your search: Created for people with ongoing healthcare needs but benefits everyone. Last medically reviewed on April 28, 2022. {"url":"/signup-modal-props.json?lang=us"}, Weerakkody Y, Ashraf A, Knipe H, et al. Noncancerous, or benign, liver lesions are common. They dont spread to other areas of your body and dont usually cause any health issues. See prior answer regarding differential for benign ones. Doctors typically provide answers within 24 hours. Myths and facts about this essential organ. If PLD starts affecting liver function or becomes too painful, surgery may be needed. Please read the disclaimer A radiologist is a medical doctor who specializes in the interpretation of imaging tests. Imaging tests: These can show where a lesion is on your liver and how big it is. Hypoattenuating hepatic nodular lesions in chronic liver disease depicted on dynamic CT have high malignant potential and should be followed with special attention to conversion from hypoattenuation to hyperattenuation to determine the optimal timing of treatment. 2000;174 (5): 1417-21. The problem arises when the concentration of triglycerides exceeds the normal levels. Liver lesions are groups of abnormal cells in your liver. . Non contrast means that no oral or IV contrast is given. 9. 3 mm hypoattenuating focus in liver. At the time the article was last revised Yuranga Weerakkody had Get new journal Tables of Contents sent right to your email inbox, September-October 2002 - Volume 26 - Issue 5, Small Hypoattenuating Lesions in the Liver on Single-phase Helical CT in Preoperative Patients With Gastric and Colorectal Cancer: Prevalence, Significance, and Differentiating Features, Articles in Google Scholar by Hyun-Jung Jang, Other articles in this journal by Hyun-Jung Jang, Current Status of Radiomics and Deep Learning in Liver Imaging, Possibility of Deep Learning in Medical Imaging Focusing Improvement of Computed Tomography Image Quality, Accuracy of Automated Liver Contouring, Fat Fraction, and R2* Measurement on Gradient Multiecho Magnetic Resonance Images, Preliminary Data Using Computed Tomography Texture Analysis for the Classification of Hypervascular Liver Lesions: Generation of a Predictive Model on the Basis of Quantitative Spatial Frequency MeasurementsA Work in Progress, Tumor Response Evaluation in Oncology: Current Update, Privacy Policy (Updated December 15, 2022). 2. In the abdomen, Hypoattenuating lesions can be found in any organs. What Causes Lesion on Liver? My mother was diagnosed with colon cancer in mid 2022 and proceeded to have full colon removal with ileostomy. Benign SLAHs were smaller (6.4 3.1 mm;P < 0.001) and more frequently had discrete margin (P < 0.001) and markedly low attenuation (P < 0.001) than metastases (9.3 2.7 mm). Only a small number of these growths are cancerous. Hyperenhancing foci on liver A 63-year-old female asked: Does 11 mm foci in liver need further follow up? However, cysts can reoccur after surgery. Lack of appetite or feeling full after eating very little food. Hepatic cyst. The majority of liver lesions are noncancerous, or benign. The presence of subcentimeter liver lesions at diagnosis was significantly associated with reduced overall survival (hazard ratio 1.65; 95% confidence interval 1.03-2.64, P = .036). Ranging from benign, to a lesion that needs monitoring (repeat imaging in 3 to 6 months), to lesions that need biopsy for diagnosis and treatment. If you are at risk or experiencing symptoms, talk to your healthcare provider. All rights reserved. Diagnostic criteria for fatty infiltration of the liver on contrast-enhanced helical CT. AJR Am J Roentgenol. Like all cancers, cancerous lesions of the liver are caused by changes to the DNA that make cells replicate uncontrollably. Getting the hepatitis B vaccine and proper treatment for viral hepatitis can lower your risk of liver cancer. In case of diffuse focal changes, the doctor reveals individual foci on the affected liver tissue, which differs from diffuse ones. Rodriguez de Lope C, Reig M, Darnell A, Forner A. Please enable scripts and reload this page. what is it? major concern or not? The criteria of SLAH were as follows: (1) 15 mm or smaller, (2) lower attenuation compared with the surrounding hepatic parenchyma, and (3) other than the dilated bile duct, periportal low attenuation, unenhanced vessels, or partial volume averaging of adjacent structures. I was found on recent ct of the abdomen with iv contrast to have hypoattenuating foci of my liver with thickening of my adrenal glands. These symptoms usually occur when a cyst starts . Hypoattenuating lesions are commonly referred to in regards to the liver or kidneys. In the liver, we can see a single or multiple hypoattenuating lesions. The most common cause of "tiny echogenic foci throughout the liver" is punctate calcification secondary to prior granulomatous infection. You can get vaccinated against hepatitis B, wear condoms when you have sex, and dont share needles if you use them to do recreational drugs. A heterogeneous liver can be caused by fatty liver disease, tumors or cirrhosis. Opportunistic Screening for Hereditary Hemochromatosis With Unenhanced CT: Determination of an Optimal Liver Attenuation Threshold. The purpose of this study was to determine the prevalence and significance of small low attenuating hepatic lesions (SLAHs) seen on helical CT in preoperative patients with gastric and colorectal cancers and to find differentiating features of benign from malignant SLAH. what is this? When this happens, you may experience abdominal pain. Theyll guide a small probe into the tumor in your liver, usually through tiny cuts in your belly. Specialized cytology/staining tests of ones pathologic specimen, requested at the time of surgery, can give prognostic information concerning tumor gr enough information to venture a guess. Your doctor may order a combination of tests to diagnose your liver lesions. Most liver metastases are multiple, involving both lobes in 77% of patients and only in 10% of cases there is a solitary metastasis. Cleveland Clinic is a non-profit academic medical center. This question is best answered by a gastroenterologist or hepatologist(liver specialist). In your case, there is not enough information provided to assess whether it is a significant finding or not. When symptoms do appear, they most commonly include: Benign tumors usually dont cause symptoms unless they grow very large. Malignant tum Dr. Heidi Fowler and another doctor agree. The parenchymal type, the most common type, is further subdivided into three subtypes: miliary, cystic, and nodular. Doctors start the process of diagnosing liver lesions by taking your medical history, considering your symptoms, and performing a physical examination. J. Cardiol. Among 881 SLAHs in 268 patients, 693 (78.3%) in 248 patients (92.5%) were benign, and 188 (21.2%) in 30 patients (11.2%) were metastases; 10 patients (3.7%) had both. Small benign lesions often dont cause symptoms and dont require treatment. Hypodense is a descriptive term used by radiologists to describe an abnormality in the liver seen on a ct scan. Conclusion: Small hypoattenuating renal masses can be characterized with reasonable accuracy by subjective impression and CT attenuation; lesions that appear solid on visual inspection or have an attenuation value of 50 HU or more are likely to be renal cell carcinoma. 4. . INTRODUCTION Liver lesions may be detected on imaging studies performed for an unrelated reason (ie, incidental liver lesion). For these, please consult a doctor (virtually or in person). We often need more information to know what the abnormality is. Had ultrasound that indicated gall stone foci (6mm). Diffusive liver changes can occur as a result of congenital pathologies (underdevelopment). 1994;49 (1): 14-8. As a tumor grows larger, it can cause liver dysfunction or problems by pushing on other tissues. The symptoms you experience depend on the type of liver lesion. Hamad S, et al. This can, Read More Does No News Mean Good News For A CT Scan Results?Continue, Please read the disclaimer It depends on what your looking for, but in general no. 2007;188 (5): 1307-12. 3. {"url":"/signup-modal-props.json?lang=us"}, Salam H, Silverstone L, Kang O, et al. Liver , Cysts , Liver neoplasms , Computed tomography (CT) , Metastases. [2] NAFLD can be categorized as nonalcoholic fatty liver (NAFL) or nonalcoholic steatohepatitis (NASH), depending on histologic features. What are the specific MRI characteristics of the lesions? The term hypoattenuating does not indicate a diagnosis but simply describes an abnormality as being darker then the normal tissues. A, Transarterial chemoembolization (TACE): This is a targeted type of chemotherapy that takes anti-cancer drugs directly to the lesion. Short description: Abnormal findings on dx imaging of liver and biliary tract The 2023 edition of ICD-10-CM R93.2 became effective on October 1, 2022. 10% of HCC is hypovascular. There are many different types of masses and they can be benign or malignant. Data is temporarily unavailable. Pathology Answer (1 of 5): The most common ultrasonic and CT abnormality that is hypotenuse is a vascular anomaly in the liver, hemangioma. All rights reserved. If it does cause problems, your symptoms will depend on the type you have. your express consent. Fatty liver disease means that you have excess fatty acids in your liver. Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other abusable medications. Most lesions can be diagnosed without the need for a tissue sample called a biopsy. The approach in this topic applies to liver lesions found incidentally in adult patients without signs or symptoms (eg, right upper quadrant pain) attributable to the lesion and without risk factors for hepatic malignancy. These types of imaging technologies help doctors diagnose issues with bones or organ tissue. We often need an ultrasound to tell what an ovarian abnormality is. Liver cirrhosis- demostrates heterogenous coarse echotexture with nodular outline, echogenic foci are seen, what does it means and need advise. An abscess was defined as a fluid-filled lesion with a thic. Connect with a U.S. board-certified doctor by text or video anytime, anywhere. These liver-specific agents are taken up into hepatocytes to varying extent (gadobenate dimeglumine 4-5%; gadoxetic acid ~50%), resulting in avid T1 enhancement of the liver parenchyma in the hepatobiliary phase, which is performed at 20 min for gadoxetic acid and about 1-2 h for gadobenate dimeglumine after contrast administration. The presence of a hypoattenuating lesion can either mean that there is a simple cyst or small sore on the surface of the organ, or it could indicate the presence of a tear or much more serious issue such as a malignant tumor. will stones get bigger? Blood tests can identify viral hepatitis infection or markers that identify liver disease. Laing RW, et al. Without more information, the answer is "Yes" & this should not be ignored. Other imaging features of these lesions help us make a diagnosis. Journal of Computer Assisted Tomography26(5):718-724, September-October 2002. CT scans can detect the additional fatty structures in the liver, which appear on the scan as areas of lighter-colored tissue, according to an article in The Oncologist. For these, please consult a doctor (virtually or in person). (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369839/), (https://www.cancer.org/cancer/liver-cancer/detection-diagnosis-staging/survival-rates.html), (https://www.cancerresearchuk.org/about-cancer/secondary-cancer/secondary-liver-cancer/about), Visitation, mask requirements and COVID-19 information.